This is a Phase II, single arm, open label clinical trial. 60 RVO patients (including 30 BRVO and 30 CRVO, respectively) are enrolled in the study. The study included a fixed treatment period (3 months) and a PRN period (6 months). In the fixed treatment period patients will receive 3 consecutive monthly intravitreal of 0.5 mg Conbercept. In the PRN period, patients are monthly visited and retreatment will be needed according to the retreatment criteria pre-specified.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
60
intravitreal injection of 0.5 mg Conbercept
Beijing Tongren hospital affiliated to Capital Medical University
Beijing, Beijing Municipality, China
The Affiliated Eye Hospital of WMC
Wenzhou, Zhejiang, China
Mean change from baseline in BCVA
Time frame: 3-month
Mean change from baseline in BCVA
Time frame: baseline to 9-month
Mean change from baseline in central retinal thickness
Time frame: baseline to 9-month
Mean injection times
Time frame: baseline to 9-month
Mean change from baseline in Macular edema volume and other anatomical character in the study eye
Time frame: baseline to 9-month
Rate of adverse event
Time frame: 3-month and 9-month
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