Clinical Trial to Evaluate ANT-1401 in Crow's Feet

Inclusion Criteria: * 30 - 60 years of age * mild to moderate Crow's Feet wrinkles (IGA 1-2) at rest * moderate to severe Crow's Feet (IGA 2-3) on contraction * moderate to severe Crow's Feet (SSA 2-3) on contraction * Have adequate vision to assess facial wrinkles in a mirror Exclusion Criteria: * botulinum toxin treatment in the prior 6 months * history of periocular surgery, brow lift or related procedures * soft tissue augmentation in the lateral canthal region in the prior 12 months * dermabrasion or laser treatment in the periocular region in the last 6 months * topical prescription-strength retinoids in the prior 3 months * present or history of neuromuscular disease * present or history of "dry eye" * systemic aminoglycoside use in the week prior to treatment application