Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization

INCLUSION CRITERIA 1. Age \>18 years 2. Patients providing written informed consent 3. Scheduled to undergo clinically-indicated non-emergent invasive coronary angiography with an ACC/AHA Class II indication EXCLUSION CRITERIA 1. Known CAD (myocardial infarction, PCI, CABG) 2. ACC/AHA Class I or III indication for ICA 3. Non-cardiac illness with life expectancy \<2 years 4. Inability to provide written informed consent 5. Concomitant participation in another clinical trial in which subject is subject to investigational drug or device 6. Pregnant women 7. Allergy to iodinated contrast agent 8. Serum creatinine ≥1.5 mg/dl or Glomerular Filtration Rate \<30 ml/min 9. Uncontrolled Baseline irregular heart rhythm (e.g., atrial fibrillation, etc.) 10. Heart rate ≥100 beats per minute 12\) Systolic blood pressure ≤90 mm Hg 13) Contraindications to β blockers or nitroglycerin 14) Known complex congenital heart disease 15) Body mass index \>35