The purpose of this study is to evaluate the efficacy and the possible mechanisms underlying music-based multitask training (i.e., Jaques-Dalcroze eurhythmics) in older people, compared to multicomponent exercise training. This study is designed as a 12-month, prospective, single-centre, single-blind, 2-arm, parallel group, randomized controlled trial in which 140 community-dwelling older adults at high risk of falls are randomly assigned to receive either a music-based multitask training intervention (i.e., Jaques-Dalcroze eurhythmics) or a multicomponent exercise training intervention, for 12 months. A 12-month follow-up is planned with outcome measures assessed at three time points: baseline (before intervention initiation), 6-month (intervention mid-point), and 12-month (intervention termination). Outcomes of interest include physical and cognitive performances, and falls. In addition, the investigators specifically address brain circuits in an exploratory sub-study. Volunteer trial participants from both study arms are invited to undergo functional magnetic resonance imaging (fMRI) at baseline and 12-month.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
142
12 months of weekly, supervised, structured, progressive, 60-min music-based multitask exercise classes (i.e., Jaques-Dalcroze eurhythmics). The music-based multitask program includes all exercises used in a previous work.
12 months of weekly, i) supervised, structured, progressive, 60-min multicomponent exercise classes, supplemented by ii) 30-min home-based exercise sessions. Briefly, the multimodal exercise program is based on core components for successful fall prevention in older adults. It contains balance, gait, coordination and strength training, with balance as a core component.
Bone Diseases Service, Geneva University Hospitals
Geneva, Switzerland
Change in gait variability under dual-task condition
Time frame: 6 months, 12 months
Change in gait performances (quantitative gait analysis under single and dual-task conditions)
Time frame: 6 months, 12 months
Change in balance performances (quantitative balance analysis)
Time frame: 6 months, 12 months
Change in functional tests performances (Timed Up & Go test and Short Physical Performance Battery)
Time frame: 6 months, 12 months
Incidence of falls and fractures (prospective daily recording using calendars, to be returned monthly)
Time frame: 6 months, 12 months
Change in cognitive performances (comprehensive neuropsychological battery assessing different aspects of executive functioning)
Time frame: 6 months, 12 months
Change in anxiety/depression (Hospital Anxiety and Depression scale)
Time frame: 6 months, 12 months
Change in fear of falling (Short-FESI)
Time frame: 6 months, 12 months
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