Use of Platelet Rich Plasma in the Management of Acute Hamstring Muscle Strain Injury

Aspetar90 enrolled

Overview

The purpose of this study is to evaluate the therapeutic benefit of utilizing complex growth factor preparations (Platelet Rich Plasma (PRP) in the management of acute hamstring injuries. The hypothesis is that the time to return to sport is shorter in the patient group treated with Complex Growth Factor Preparations (PRP) in combination with exercise therapy in comparison with 2 control groups: * the patient group treated with Platelet Poor Plasma (PPP) injections in combination with exercise therapy (control injection AND usual care). * the patient group treated with exercise therapy (usual care)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Acute Hamstring Muscle Strain Injury

Interventions

Eligibility

Sex: MALEMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Acute onset posterior thigh pain * MRI confirmed Grade I, II hamstring lesions * \< 5 days from injury * Able to perform Physiotherapy at ASPETAR (5 sessions/week) * Available for follow-up * Male * Age \> 18 years Exclusion Criteria: * Diabetes, immuno-compromised state * Overlying skin infection * Re-injury or Chronic ongoing hamstring injury * Unwilling to comply with follow up * Contraindication to MRI * Needle Phobia * Bleeding disorder or other medical contraindication to injection * Medication increasing bleeding risk (e.g. Plavix) * Concurrent other injury inhibiting rehabilitation

Outcomes

Primary Outcomes

Time to Return to Play

Time to return to full sports activity; either training or match play.

Time frame: Patients will be followed for the duration of time to return to play with an expected average of 27 days and up to 1 year.

Secondary Outcomes

Recurrent hamstring lesions.

Time frame: 2 months after return to play, 1 year after return to play.