Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities

Dr. Sami Ulus Children's Hospital81 enrolled

Overview

Experimental and observational studies have shown that vitamin D deficiency may be associated with an increased risk for non-bone diseases and/or abnormal development for the other systems of fetus. The aim of this study is to determine the relationship between cord blood 25-hydroxyvitamin D (25 (OH) D) concentrations and the subsequent risk of morbidities including RDS, PDA, NEC, BPD AND ROP in preterm infants.

It was shown that vitamin D play important role in the pathogenesis of long term morbidities of newborn. Experimental and observational studies have shown that vitamin D deficiency may be associated with an increased risk for non-bone diseases and/or abnormal development for the other systems of fetus. The aim of this study is to determine the relationship between cord blood 25-hydroxyvitamin D (25 (OH) D) concentrations and the subsequent risk of morbidities including RDS, PDA, NEC, BPD AND ROP in preterm infants.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Respiratory Distress Syndrome

Eligibility

Sex: ALLMin age: 1 DayMax age: 5 Days

Medical Language ↔ Plain English

Inclusion Criteria: * infants \<32 weeks of gestational age Exclusion Criteria: * infants with major congenital abnormality * infants \>32 weeks of gestational age

Locations (1)

Sami Ulus CH

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Respiratory Distress Syndrome

The association of vitamin D level with respiratory distress syndrome

Time frame: three days

Secondary Outcomes

Sepsis

Association of vitamin D level with sepsis

Time frame: four weeks

Data from ClinicalTrials.gov

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