Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives

Inclusion criteria: * Male or non-pregnant female ≥18 years of age * Malignant or non-malignant opioid sensitive pain * Must sign an informed consent form (ICF) * Must have a stable daily dose of oxycodone prolonged release formulation titrated to analgesic effect (as to be assessed by clinical experts) * Use of laxatives for concomitant opioid-induced constipation in an adequate dose and length of time and without sufficient effect * BFI ≥30 and state a discomfort caused by the constipation at screening * Ability to answer the patient questionnaires and have an estimated overall life expectancy of at least six (6) months Exclusion criteria: * History of, or on-going, abuse of alcohol and/or drugs * Inability to read and understand written instructions, ICF or questionnaires * Constipation not related to opioid use * Unsuitable patient for other reason(s) in the opinion of the investigator * Inpatients, if admission and/or discharge is expected during study period