When using nitrous oxide for general anesthesia, nitrous oxide diffusion induces intracuff hyperinflation of the endotracheal tube. Furthermore the difference among various types of cuffed endotracheal tubes in cuff pressure behavior during nitrous oxide exposure. TaperGuard(TM) tube has been newly introduced and has tapered-shape cuff. In vitro study, the intracuff pressure of TaperGuard(TM) tube was lower than that of conventional tube with cylindrical-shaped cuff of the conventional tube(Hi-Lo(TM) tube). Therefore, this clinical study is needed to evaluate the intracuff pressure during general anesthesia with nitrous oxide exposure.
During 60 minutes after routine anesthetic induction and intubation of the endotracheal tubes, intracuff pressures will be measured every 10 minutes with a manometer (VBM, Sulz, Germany). 60% nitrous oxide will be added at time 0. For 60 minutes from the beginning of general anesthesia, intracuff pressures will be measured every 10 minutes. After 60 minutes, Intracuff pressures will be maintained around 20 cm H2O during the remaining period of the surgery. The questionnaire for a sore throat, hoarseness, and dysphagia will be questioned at about 1, 6, and 24 hours after the surgery and the general anesthesia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
TRIPLE
Enrollment
38
Randomized allocation of the endotracheal cuffs for general anesthesia, mechanical ventilation will be maintained with Mallinckrodt Hi-Lo(TM) endotracheal tube.
Randomized allocation of the endotracheal cuffs for general anesthesia, mechanical ventilation will be maintained with Mallinckrodt TaperGuard(TM) endotracheal tube.
Dongguk University Ilsan Hospital
Goyang, Gyeonggido, South Korea
Intracuff pressure of the endotracheal tube after 60 min (1 hour) with exposure to nitrous oxide
Time frame: One hour after the exposure to nitrous oxide under general anesthesia
Intracuff pressure of the endotracheal tubes
Intracuff pressures will be measured with a manometer (VBM, Sulz, Germany)
Time frame: 0, 10, 20, 30, 40, 50 minutes after exposure to nitrous oxide
Postoperative sore throat: incidence
Time frame: About 1, 6, 24 hours after termination of anesthesia
Postoperative hoarseness: incidence
Time frame: About 1, 6, 24 hours after termination of anesthesia
Postoperative dysphagia: incidence
Time frame: About 1, 6, 24 hours after termination of anesthesia
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