Mechanism of Action of Milk and Its Components on Glycemic Control in Healthy Young Men

University of Toronto12 enrolled

Overview

The investigators hypothesize that the physiological effects of milk on satiety and glycemic control are mediated by the interaction between its macronutrient components by both insulin-dependent and independent mechanisms.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Enrollment

Conditions

Glycemic Control Gastrointestinal Hormone Response Healthy Young Men

Interventions

Milk FatDIETARY_SUPPLEMENT

Milk ProteinDIETARY_SUPPLEMENT

LactoseDIETARY_SUPPLEMENT

Whole milk (3.25% M.F.(OTHER

Commercially available milk from the grocery store

Eligibility

Sex: MALEMin age: 20 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy young men * 20-30 years of age * BMI: 20-24.9 kg/m2 Exclusion Criteria: * Smoking * Dieting * Skipping breakfast * Lactose intolerance or allergies to milk * Taking medications that may affect glucose metabolism or appetite * Diabetes (fasting blood glucose ≥ 7.0 mmol/L) or other metabolic diseases

Locations (1)

University of Toronto

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

Glucose

Time frame: 0-180 min

Secondary Outcomes

Insulin

Time frame: 0-180 min

Data from ClinicalTrials.gov

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