Aim is to investigate the influence of an early supply of parenteral nutrition including a fish oil containing lipid emulsion on the course of acute lung injury in the intensive care unit. In comparison, a standard parenteral nutrition with a soybean oil based emulsion will be used. Data obtained in this trial may provide evidence for a beneficial effect of fish oil derived omega-3 fatty acids in parenteral nutrition regarding their influence on acute lung injury.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
1
Lipoplus 20% (MCT/LCT/FO) i.v. lipid emulsion for parenteral nutrition
Lipofundin N 20% (LCT, soy bean oil) i.v. lipid emulsion for parenteral nutrition
University Clinic Giessen
Giessen, Germany
change in blood oxygenation (PaO2/FiO2ratio)
Time frame: change day 1 to day 6
Triglycerides
Time frame: day 1 to day 16
Sequential Organ Failure Assessment
Time frame: day 1 to day 28
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