Study to Determine the Absorption, Metabolism, and Excretion of [14C]LX4211 in Healthy Male Subjects

Inclusion Criteria: * Adults ≥18 to ≤55 years of age * Vital signs at Screening in the following ranges: systolic blood pressure, 90-140 mm Hg; diastolic blood pressure, 50-90 mm Hg; heart rate, 50-100 bpm * Body mass index (BMI) ≥18 and ≤35 kg/sq m * Historically able to produce a minimum of 1 bowel movement per day * Willing and able to provide written informed consent Exclusion Criteria: * Female * Receipt of any investigational drug within 30 days prior to Dosing, or investigational protein or antibody-based therapeutic agents within 3 months prior to Screening * Prior exposure to LX4211 * Use any tobacco product within 2 months prior to Screening and while participating in the study (Day -1 through Discharge) * History of bariatric surgery or any other GI surgery that may induce malabsorption * History of any major surgery within 6 months prior to Screening * History of renal or hepatic disease, or significantly abnormal kidney or liver function tests at Screening * History of any clinically relevant psychiatric, renal, hepatic, pancreatic, cardiovascular, neurological, hematological, or GI abnormality * History of any active infection within 14 days prior to Dosing * History of alcohol or substance abuse within 2 years prior to Dosing * History of human immunodeficiency virus (HIV), hepatitis B, or hepatitis C * Donation or loss of \>400 mL of blood or blood product within 3 months of Dosing * Positive urine glucose at Screening * Positive urine screen for drugs of abuse at Screening or Day -1 * Positive breath test for alcohol at Screening or Day -1 * Participation in \>1 other radiolabeled investigational study drug trial within 12 months prior to Day -1 * Exposure to significant radiation within 12 months prior to Day -1