The aim of the study is to assess the beneficial effect of the short term consumption of the highly mineralized bicarbonated sodium water on blood lipid parameters compared to a low mineralized water.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
162
1,25 liter a day at the mealtimes
OPTIMED
Gières, France
Naturalpha
Lille, France
Biofortis
Saint-Herblain, France
Fasting plasma triglyceride
Time frame: 4 weeks
Fasting plasma total cholesterol
Time frame: 4 and 8 weeks
Fasting plasma triglyceride
Time frame: 8 weeks
Incremental Area Under Curve (iAUC) between T0 and T480min of plasma triglycerides
Time frame: 0 and 8 weeks
Fasting plasma High Density Lipoprotein cholesterol
Time frame: 4 and 8 weeks
Fasting plasma Low Density Lipoprotein cholesterol
Time frame: 4 and 8 weeks
Fasting plasma glucose
Time frame: 4 and 8 weeks
Heart rate
Time frame: 4 and 8 weeks
Systolic Blood Pressure
Time frame: 4 and 8 weeks
Diastolic Blood Pressure
Time frame: 4 and 8 weeks
Incremental Area Under Curve (iAUC) between T0 and T480min of plasma total cholesterol
Time frame: 0 and 8 weeks
Incremental Area Under Curve (iAUC) between T0 and T480min of plasma High Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
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Incremental Area Under Curve (iAUC) between T0 and T480min of plasma Low Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Cmax between T0 and T480min of plasma triglyceride
Time frame: 0 and 8 weeks
Cmax between T0 and T480min of plasma High Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Cmax between T0 and T480min of plasma total cholesterol
Time frame: 0 and 8 weeks
Cmax between T0 and T480min of plasma Low Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Delta peak between T0 and T480min of plasma Low Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Delta peak between T0 and T480min of plasma High Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Delta peak between T0 and T480min of plasma total cholesterol
Time frame: 0 and 8 weeks
Kinetic between T0 and T480min of plasma Low Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Kinetic between T0 and T480min of plasma High Density Lipoprotein cholesterol
Time frame: 0 and 8 weeks
Kinetic between T0 and T480min of plasma total cholesterol
Time frame: 0 and 8 weeks
Kinetic between T0 and T480min of plasma triglycerides
Time frame: 0 and 8 weeks
Delta peak between T0 and T480min of plasma triglycerides
Time frame: 0 and 8 weeks
Alanine Amino Transferase
Time frame: 4 and 8 weeks
Aspartate Amino Transferase
Time frame: 4 and 8 weeks
Plasmatic urea
Time frame: 4 and 8 weeks
Plasmatic creatinine
Time frame: 4 and 8 weeks
Plasmatic potassium
Time frame: 4 and 8 weeks
Plasmatic sodium
Time frame: 4 and 8 weeks
Plasmatic Chloride
Time frame: 4 and 8 weeks
Gamma Glutamyl Transferase
Time frame: 8 weeks
Bilirubin
Time frame: 8 weeks
Complete blood count
Time frame: 8 weeks