Clinical Outcomes of Methicillin Resistant Staphylococcus Aureus (MRSA) Hospital-Based Pneumonia

Time to Therapy Change

Time to therapy change was calculated from initiation of therapy (index date) to change in therapy (event date). Therapy change was defined as the discontinuation of linezolid or vancomycin and initiation of a different agent with activity against MRSA (clindamycin, daptomycin, doxycycline, linezolid, minocycline, tigecycline, trimethoprim/sulfamethoxazole, vancomycin). As such, therapy change included switching from linezolid to vancomycin, switching from vancomycin to linezolid, or switching from either linezolid or vancomycin to another anti-MRSA antibiotic.

Time frame: Baseline (1 January 2001) up to 3559 Days (30 September 2010)

Time to Discharge From the Hospital

Time to discharge from hospital was calculated from initiation of therapy (index date) to hospital discharge (event date).

Time frame: Baseline (1 January 2001) up to 3559 Days (30 September 2010)

Time to Transfer Out From the Intensive Care Unit (ICU)

Time to discharge from the ICU was calculated from the initiation of therapy (index date) to the time the participant was transferred out from ICU (event date). Transfer out of an ICU was assessed among those participants who had initiated linezolid or vancomycin therapy in the ICU.

Time frame: Baseline (1 January 2001) up to 3559 Days (30 September 2010)

Time to Intubation

Time to intubation was calculated from the initiation of therapy (index date) to intubation (event date).

Time frame: Baseline (1 January 2001) up to 3559 Days (30 September 2010)