The purpose of this study is to estimate the differences between albuminuria values determined as Urine Albumin-to-Creatinine Ratio (UACR)(log transformed) from baseline to last observation caused by paricalcitol between the group of control and group of treatment.
Clinical Trial to estimate UACR determined albuminuria differences between treatment and non-treatment groups from basal intake to last study-related observation. Patients should suffer proteinuric Chronical Kidney Disease and recovered levels of seric 25(OH)D. Also, this clinical trial tries to determinate the effect of paricalcitol over several metabolic and inflammatory parameters on patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
127
Oral paricalcitol, 1 ug/day, plus daily treatment. 6 months (all study)
Daily treatment is not define by protocol, because daily treatment in CKD is highly variable and includes salt and/or blood pressure regulation, angiotensine system stoppers, controlled diet, etc.
Hospital Universitario General de Alicante
Alicante, Alicante, Spain
Albuminuria in proteinuric Chronical Kidney Disease patients
Estimate differences between groups based on albuminuric level determined as UACR from basal to last observation visit.
Time frame: 1 year
Change from baseline albuminuria at 6 months
Determinate % of patients with an over 20% of albuminuria descent from baseline
Time frame: 6 months
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