Manipulation of Dietary Protein and the Anabolic Response

N/ACompletedNCT01820975

Maastricht University Medical Center28 enrolled

Overview

In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Focus: Anabolic Response to Food Intake in Young Individuals Condition Relevance: Skeletal Muscle Health, Sarcopenia

Interventions

High protein intakeDIETARY_SUPPLEMENT

Placebo comparatorOTHER

No protein intake

Eligibility

Sex: MALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Males * Aged between 18-35 years * Healthy, recreationally active * BMI \< 30 kg/m2 Exclusion Criteria: * Smoking * Allergies to milk proteins (whey or casein) * Vegetarians * Diagnosed GI tract diseases * Female * Arthritic conditions * A history of neuromuscular problems * Previous participation in amino acid tracer studies * Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications

Outcomes

Primary Outcomes

Muscle protein fractional synthetic rate following protein ingestion

The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion.

Time frame: 3 hours

Data from ClinicalTrials.gov

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