Echocardiography in Kids Intensive Care Decision Support

Imperial College London25 enrolled

Overview

A study to determine if echocardiographically derived parameters, plethysmographic variability index and pulse pressure variation predict fluid responsiveness in children on PICU.

A study to determine if echocardiographically derived parameters, plethysmographic variability index and pulse pressure variation predict fluid responsiveness in children on PICU. These parameters will be measured pre and post fluid bolus in children prescribed fluid bolus therapy for clinical indications on the PICU. Children will be classified as responders (\>10% increase in cardiac output) and non responders (\<10% increase). Appropriate statistical tests will be performed to determine the most useful predictor of an increase in cardiac output following a fluid bolus.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Fluid Responsiveness Cardiac Output

Interventions

Ultrasound cardiac output measurementOTHER

Eligibility

Sex: ALLMax age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Any ventilated child requiring fluid bolus therapy on the PICU for clinical indications Exclusion Criteria: * Arrythmia * Intracardiac shunt

Locations (1)

Imperial College Healthcare NHS Trust

London, United Kingdom

Outcomes

Primary Outcomes

Fluid responsiveness

10% increase in cardiac output following fluid bolus

Time frame: Immediate

Data from ClinicalTrials.gov

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