Effects of Maternal Body Composition on Offspring Brain Structure and Function

N/AActive Not RecruitingNCT01822067

Arkansas Children's Hospital Research Institute100 enrolled

Overview

The specific aim of this study is to use MRI methods to evaluate and compare brain structure and function in two groups of full-term neonates at two-weeks of age: those born of obese mothers and those born to normal weight mothers.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Brain Function

Eligibility

Sex: ALLMin age: 11 DaysMax age: 17 DaysHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * the participant must be enrolled in the Arkansas Children's Nutrition Center (ACNC) Glowing study and be about 2 weeks of age +/- 3days Exclusion Criteria: * none specified

Locations (1)

Arkansas Children's Nutrition Center

Little Rock, Arkansas, United States

Outcomes

Primary Outcomes

Brain Structure

We will use high resolution volumetric magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) to measure the brain structure of 2 week old infants

Time frame: Age 2 weeks

Secondary Outcomes

Brain Function

We will use high resolution Resting state functional magnetic resonance imaging (rsfMRI) to measure the brain function of 2 week old infants

Time frame: Age 2 weeks

Data from ClinicalTrials.gov

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