Lung Volume Reduction Coil Treatment in Emphysema.

Inclusion Criteria: * Bilateral emphysema on Chest CT Scanner * Post bronchodilator FEV1 \< 50 % * Total Lung Capacity \> 100 % * Residual Volume \> 220 % * Dyspnea score between 2 and 4 based on the mMRC scale * Stopped cigarette smoking for more than 8 weeks * Pulmonary rehabilitation within the previous twelve months * Consent form signed * Covered by Medical Insurance Exclusion Criteria: * Post bronchodilator FEV1 \< 15% * Post-bronchodilator change in FEV1 \> 20% * Severe recurrent respiratory infections requiring more than 2 hospitalization stays within the past twelve months * COPD exacerbation requiring hospital stay within 3 months * Pulmonary Hypertension (Pulmonary systolic pressure \>50 mmHg on cardiac echo) * Patient unable to perform a 6-min walking test in room air * Giant bulla of more than 1/3 of the lung field on Chest CT * Strictly homogeneous emphysema on Chest CT * Clinically significant bronchiectasis * Past history of lobectomy, lung volume reduction surgery, lung transplantation * Any extrapulmonary diseases compromising survival or evaluation within the protocol (severe cardiac disease, severe renal insufficiency, cancer…) * Lung carcinoma or pulmonary nodule on CT scan requiring Chest CT scan follow-up * Contra-indication to general anesthesia * Oral anticoagulant treatment (antivitamin K) * Allergy to nitinol * Inclusion in an other study assessing respiratory treatments * Patient protected by the law