Effects of AN69 ST Hemofilter on Coagulation During Continuous Renal Replacement Therapy in Critically Ill

Zhongda Hospital40 enrolled

Overview

Compared with AN69 hemofilter, AN69 ST hemofilter may prolong the time of hemofilter and decrease the quantity of heparin during continuous renal replacement therapy in critically ill.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Critically Ill Acute Kidney Injury Septic Shock

Interventions

AN 69 ST hemofilterDEVICE

AN 69 hemofilterDEVICE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age\> 18 years old * admitted to ICU and need CRRT * anticipated survival time \>72h Exclusion Criteria: * allergy to hemofilter or heparin * heparin associated thrombocytopenia * pregnancy or lactation * using other anticoagulate drugs

Locations (1)

Xiaohua Qiu

Nanjing, Jiangsu, China

RECRUITING

Outcomes

Primary Outcomes

The using time of hemofilters

The time from the beginning of continuous renal replacement therapy until to the end when continuous renal replacement therapy had to be finished because of clotting or other reasons

Time frame: 72h

Secondary Outcomes

activated partial thromboplastin time

Heparin will be used according to activated partial thromboplastin time, and the quantity will be recorded.

Time frame: every 6h from the begining of continuous renal replacement therapy,up to 72h

Central Contacts

Qiu Xiaohua

CONTACT

02583262553 xiaohua0917@163.com

Data from ClinicalTrials.gov

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