Patients patients enrolled in this study have a Lymphoma caused by EBV (after bone marrow transplantation, organ transplantation or patient immunodeficient. They will receive one to three injections of allogenic CTL specific EBV. The purpose of this study is to ensure that these injections can not cause a GVH and to study what the side effects are and to see whether this therapy might help patients with Lymphoma. Immunological monitoring will also be studied.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
18
CHU de Bordeaux
Bordeaux, France
CHU de Brest
Brest, France
CHU de Lille
Lille, France
CHU de Limoges
Limoges, France
CHU de Nantes
The safety of one to three injections of allogenic EBV specific CTLs will be determined through adverse event measurement
Time frame: 3 months post last injection
To determine the survival, and anti-tumor effects of EBV specific cytotoxic T-lymphocyte lines.
Time frame: 1 year
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Nantes, France
Hopital Pitié Salpétrière
Paris, France
Hôpital Necker
Paris, France