Improving Sensitivity of Urine Cytology for Bladder Cancer

Johns Hopkins University

Overview

Can a commercially available vibrating chair increase the number of urothelial cells in a urine sample of healthy participants non-invasively? The investigators plan is participants will alternate 15 minutes of drinking eight fluid ounces of water and 15 minutes of sitting in the vibrating chair for one hour. The control group will alternate 15 minutes of drinking eight fluid ounces of water and 15 minutes of sitting in a non-vibrating chair for one hour. Then, urine samples will be collected and examined for urothelial cell concentration for both groups.

Study Type

INTERVENTIONAL

Allocation

Purpose

SCREENING

Masking

SINGLE

Conditions

Bladder Cancer

Interventions

La-Z-Boy Massage Chair Vibration Effect on Bladder Cancer Cell ConcentrationDEVICE

Eligibility

Sex: MALEMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Only adult male subjects who will not have surgery within a period of 2 weeks. * Over the age of 18 * Have had a confirmed diagnosis of stage 0-4 transitional cell carcinoma within the last 30 days Exclusion Criteria: * Cognitive impairment resulting in the inability to give informed consent * Lack of spoken and written English resulting in the inability to give informed consent * Presence of infectious disease * Insulin dependent diabetes mellitus * Endogenous osteosynthetical material implants * Knee or hip prosthesis * Pacemaker * Epilepsy * Musculo-skeletal disorders * Weight in excess of 250 pounds * Poor circulation

Locations (1)

Johns Hopkins Hospital

Baltimore, Maryland, United States

Outcomes

Primary Outcomes

Number of Cancer Cells

Number of Cancer Cells in a 50 ml Urine

Time frame: up to 24 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.