Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation

Gachon University Gil Medical Center60 enrolled

Overview

The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.

Laparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in haemodynamic variables, regional cerebral oxygen saturation, and early postoperative cognitive function in patients undergoing laparoscopic gastrectomy in the reverse Trendelenburg position with those patients that underwent conventional open gastrectomy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pneumoperitoneum

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA class I or II, aged 20 to 70 yrs Exclusion Criteria: * Patients with morbid obesity (body mass index \> 30 kg/m2) or a history of cerebrovascular or respiratory disease were excluded.

Locations (1)

Gachon University Gil Medical Center

Incheon, South Korea

Outcomes

Primary Outcomes

MMSE

5 days after operation MMSE (mini-mental status exam)was recorded

Time frame: 5days after end of surgery

Data from ClinicalTrials.gov

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