Noninvasive Positive Airway Pressure Ventilation and Risk of Facial Pressure Ulcers

Ospedale S. Giovanni Bosco170 enrolled

Overview

To assess risk of skin pressure lesions in patients treated with noninvasive mechanical ventilation.

Noninvasive ventilation improves the outcome of patients with acute respiratory failure; however patient's discomfort may be responsible for up to a fifth of failures. Scant literature exists on NIV-related pressure ulcers and their determinants. Aim of the study is to seek for determinants, if any, associated with the development of pressure ulcers related to noninvasive ventilation. Study design: observational. Patients treated with NIV from December 2009 to December 2011 will be analyzed. Main end-points: to seek for variables associated to the development of NIV-related pressure ulcers in patients with acute respiratory failure.

Study Type

OBSERVATIONAL

Enrollment

170

Conditions

Acute Respiratory Failure

Interventions

Noninvasive ventilation maskDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * severe dyspnea at rest * respiratory rate \> 30 per minute * PaO2/FiO2 \< 200 (despite oxygen with Venturi with a FiO2 og 0.5) * use of accessory respiratory muscles * pH \< 7.35 \> 7.10 Exclusion Criteria: * STEMI * NSTEMI/Unstable angina * Hemodynamic instability * Need for immediate endotracheal intubation * Inability to protect the airways * Impaired sensorium * Pulmonary embolism * Gastrointestinal bleeding * Hematological malignancy or neoplasms with ECOG performance status \> 2

Locations (1)

Medicina d'Urgenza - Terapia Subintensiva. Ospedale S. Giovanni Bosco

Torino, Torino, Italy

Outcomes

Primary Outcomes

Risk of skin pressure ulcers in patients treated with noninvasive ventilation for acute respiratory failure.

Skin lesions were classified as follows: * reddening, * loss of skin integrity, * necrotic lesion.

Time frame: Risk of pressure ulcers within 72 hours from noninvasive ventilation beginning.

Secondary Outcomes

Incidence of skin pressure ulcers in patients treated with noninvasive ventilation.

Characterization of skin lesions during noninvasive ventilation in patients with acute respiratory failure.

Time frame: Incidence of skin pressure ulcers. Patients will be followed during duration of high dependency unit stay for an average length of stay of 7 days.

Data from ClinicalTrials.gov

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