Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

Inclusion Criteria: 1. AML as defined by the WHO diagnostic criteria 2. Age \< 19 years at time of diagnosis 3. Written informed consent Exclusion Criteria: 1. Previous chemotherapy or radiotherapy. This includes patient with secondary AML after previous cancer therapy 2. AML secondary to previous bone marrow failure syndrome. 3. Down syndrome (DS) 4. Acute promyelocytic leukaemia (APL) 5. Myelodysplastic syndrome (MDS) 6. Juvenile Myelomonocytic Leukaemia (JMML) 7. Known intolerance to any of the chemotherapeutic drugs in the protocol. 8. Fanconi anaemia 9. Major organ failure precluding administration of planned chemotherapy. 10. Positive pregnancy test 11. Lactating female or female of childbearing potential not using adequate contraception