Cerament Treatment of Fracture Defects

Inclusion Criteria: * patients with traumatic, closed, depression fracture of the proximal tibia (limited to AO type B2 \& B3) * solitary trauma * candidate for bone grafting * patients between the age of 18 and 65 years * written informed consent obtained before any study-related activities * patients with communicative ability to understand the procedure and participate in the study and comply with the follow up program Exclusion Criteria: * patients with multiple injuries * polytrauma patients * compartment syndrome * previous iliac crest bone graft harvesting * local infection at the site of implantation * chronic pain disease * malignancy * rheumatoid arthritis * chronic cortisone intake * X-ray diagnostics not available, fracture cannot be classified * clinically significant or unstable medical or surgical condition that may preclude safe and complete study participation * a pre-existing calcium metabolism disorder (e.g. hypercalcemia) * known hyperthyroidism or autonomous thyroid adenoma * history of serious reaction to iodine based radio contrast agents * women who are pregnant or breastfeeding * irreversible coagulopathy or bleeding disorder * history of physical or psychological condition that contraindicates the use of an investigational device or render the patient at high risk from treatment complications * history of hypersensitivity to the investigational device or any of its ingredients * participation in other clinical trials during the present clinical trial or within the last 1 month