Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals

Inclusion Criteria: * Male * 18-40 years * Healthy * signed consent form Exclusion Criteria: * Blood pressure \> 140/90 mmHg * Had suffered a myocardial infarction or stroke * Suffers from any blood-clotting disorder * Suffers from any metabolic disorders (e.g. diabetes or any other endocrine or liver diseases) * Any dietary restrictions or on a weight reducing diet * Allergies or intolerances to any foods * Smoker * Heavy drinker (\>21 units per week) * On any lipid-modifying medication * On any blood pressure lowering medication * On any medication affecting blood clotting * Taking high dose fish oil supplements (greater then 1 g EPA and DHA per day) or high doses of antioxidant vitamins (greater then 800 μg vitamin A, 60 mg vitamin C, 10 mg vitamin E or 400 μg beta carotene) * Taking probiotics, prebiotics, synbiotics, antibiotics or anti-inflammatory or blood lowering medication within a 2-month period prior to the study * Planning on altering consumption of vitamin supplements/fish oil capsules during the course of the study * Undertakes strenuous exercise \> 4 times per week for \> 1 hour per session * Haemoglobin levels below reference range provided by the Royal Berkshire Hospital