Irritable bowel syndrome (IBS) is a chronic gastrointestinal illness of unknown cause whose symptoms include abdominal pain, bloating and altered bowel pattern. Diet has been shown to influence the bacteria gut interaction. Our aim is to determine if components of the diet affect IBS symptoms by changing the bacteria gut interaction. In particular, we will measure whether after being on a diet high or low on certain factors there is a change in the timing and amount of hydrogen and methane produced by bacteria digesting lactulose and on IBS symptom severity.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
30
Hotel Dieu Hospital
Kingston, Ontario, Canada
Area under the Curve of Hydrogen Gas on Lactulose Breath Test
Time frame: 5 hours
Change in Area Under the Curve on Lactulose Breath Test from Baseline
Time frame: 5 hours
Change in IBS Symptom Severity Score from Baseline
Time frame: 3 weeks
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