This was a Non-interventional Prospective Study. Centres enrolled adult patients with partial-onset seizures with or without secondary generalisation for whom the clinician had decided to initiate Eslicarbazepine Acetate (ESL) as an adjunctive therapy prior to the decision to take part in this study. Patients enrolled into the study were not sufficiently controlled with one drug licensed for the use as monotherapy in partial-onset seizures. Patients were seen at baseline and then during normal clinical visits at intervals. Patients in this study were assessed for efficacy and tolerability at baseline and then at least 3 and 6 months after the baseline.
Study Type
OBSERVATIONAL
Enrollment
254
The Eslicarbazepine Acetate (ESL) Summary of Product Characteristics (SPC) recommended a starting dose of 400 mg once-daily (QD) which was increased to 800 mg QD after one or two weeks. Based on individual response, the dose was increased to 1200 mg QD. Treatment decisions were made by clinicians in agreement with the participant, and were independent of participation in the study.
Unnamed facility
Hradec Králové, Czechia
Unnamed facility
Kroměříž, Czechia
Unnamed facility
Prague, Czechia
Unnamed facility
Aalborg, Denmark
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Arhus C, Denmark
Unnamed facility
Copenhagen, Denmark
Retention Rate of Eslicarbazepine Acetate (ESL) After 6 months from Baseline
Time frame: 6 months
Change in Overall Seizure Frequency after 3 and 6 months from Baseline
Change in overall seizure frequency calculated as absolute and percent changes after 3 and 6 months from baseline compared to the seizure frequency 3 months before introduction of ESL.
Time frame: Baseline, 3 months and 6 months
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Unnamed facility
Dianalund, Denmark
Unnamed facility
Esbjerg, Denmark
Unnamed facility
Glostrup Municipality, Denmark
Unnamed facility
Holstebro, Denmark
...and 96 more locations