Stenting for Symptomatic Intracranial Artery Stenosis Registry in China

Inclusion Criteria: * 18-80 year old * medical failure patient with systematic Intracranial artery stenosis * More than 3 weeks after most recent ischemic stroke * Digital Subtraction Angiography(DSA) showed ≥70% stenosis in target intracranial artery * Imaging test within 1 week showed bad collateral circulation in target vessel area * Diseased vessel diameter≥2mm, length \<15mm, distal vessel is normal Exclusion Criteria: * Diffused intracranial stenosis * Acute stroke or TIA within 3 weeks * Pure penetrating branch stenosis showed by cerebral imaging * Non-atherosclerosis pathology for the stenosis * Intracranial hemorrhage in target vessel area within 6 weeks; or potential cardiac thrombus source * Intracranial tumor, arterial aneurysm or intracranial arteriovenous malformation •\>50% stenosis in extracranial carotid artery or vertebral artery in operation side; Known contradiction to heparin, aspirin, clopidogrel, anesthesia or contrast; hemoglobin \<10g/dl，platelet count \<100000 * Modified Rankin score ≥3 related to target vessel; * INR(International Normalized Ratio)\>1.5(irreversible），persist hemorrhage risk; life expectancy \< 1year * Pregnant or beast-feeding * Not suitable for endovascular stenting judged by Indication Judgement Committee