Molecular Mechanism of POP Kidney Yin Deficiency Syndrome From the Interventional Effects of CLCF1

Inclusion Criteria: * The Participants who volunteer to be test subjects, and can accept experimental drugs, and promise to finish the course should sign the informed consent. * Female ages 45 to 75 had gone through natural menopause before two years * In accordance with the western medicine diagnostic criteria of osteoporosis and belong to kidney Yin deficiency syndrome differentiation of traditional Chinese medicine certificate; * In accordance with the western medicine diagnostic criteria; * In accordance with TCM diagnostic methods; .If any of the above answers are no, The subjects couldn't in the study. Exclusion Criteria: * Do not accord with standard of the western medicine diagnosis and TCM diagnostic methods * Age: \<44 and \> 76 years old; * With hyperparathyroidism, osteomalacia, rheumatoid arthritis, multiple myeloma and other serious complications such as secondary osteoporosis; Late or deformity, disability, loss of labor; * With cardiovascular, cerebrovascular, liver, kidney and hematopoietic system and other serious primary diseases; * Psychosis or alzheimer's patients; * Nearly three months, the use of hormone replacement therapy (HRT) and taking calcitonin, nearly six months has used double phosphonic acid salt for 15 days, etc.; * This medicine allergic constitution or composition of known to have allergies; * In a critical condition, It's difficult to make exact evaluators to efficacy and safety of the new drugs;