Prostatic Artery Embolization for Benign Prostatic Hyperplasia

Saskatchewan Health Authority - Regina Area13 enrolled

Overview

To evaluate whether Prostatic Artery Embolization (PAE) might be an effective alternative treatment option for benign prostatic hyperplasia (BPH), in comparison to current gold standard surgical treatment- Transurethral Resection of Prostate (TURP).

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Benign Prostate Hyperplasia

Interventions

Prostate artery embolizationPROCEDURE

Eligibility

Sex: MALE

Medical Language ↔ Plain English

Inclusion Criteria: 1. Moderate to severe lower urinary tract symptoms (i.e. International prostate symptom score IPSS\>8) who are bothered by their symptoms (i.e., interfere with the daily activities of living) 2. Urinary retention (related to BPH) leading to catheterization. 3. Refractory to medical treatment or patient is not willing to consider medical treatment 4. Pre trans-urethral resection of prostate (TURP) to reduce the size of prostate gland if prostate is too big for TURP surgery. Exclusion Criteria: 1. Mild symptoms (IPSS \<8) 2. Moderate to severe lower urinary tract symptoms (i.e. IPSS\>8) who are not bothered by their symptoms (i.e., symptoms do not interfere with the daily activities of living). 3. Suspected malignancy. 4. Any of the following clearly related to BPH- bladder stones, recurrent UTIs, and renal insufficiency. 5. Advanced atherosclerosis and unsuitable vascular access. 6. Allergy to intravenous contra

Locations (1)

Regina General Hospital

Regina, Saskatchewan, Canada

Outcomes

Primary Outcomes

Change from baseline in symptom severity at 1, 3, 6 and 12 months follow-up, as measured by International prostate symptoms score (IPSS).

Time frame: 1, 3, 6 and 12 months

Data from ClinicalTrials.gov

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