* The purpose of this study is to determine the efficacy and safety of an evaluation strategy based on utilization of high sensitivity cardiac troponin T (hscTnT), followed by coronary computed tomography angiography (CCTA) in patients with low-intermediate risk chest pain consistent with a possible acute coronary syndrome compared to a standard of care (SOC) strategy. * Unicentric, randomized, controlled, open label clinical trial that will compare a fast strategy (hscTnT followed by CCTA) with a SOC strategy (serial ECG and cardiac biomarkers followed by stress/rest imaging study).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
101
High sensitivity troponin T followed by computed coronary tomography angiography
Standard of care strategy: serial electrocardiograms and cardiac biomarkers followed by stress/rest cardiac imaging study
Hospital de la Santa Cruz y San Pablo
Barcelona, Barcelona, Spain
All cause mortality, new myocardial infarction, new unstable angina, new heart failure, new hospital admission, new consult to the Emergency Department
Composite end-point.
Time frame: 1 month after index event
All cause mortality
Time frame: 1 month
Myocardial infarction
Time frame: 1 month
Unstable angina
Time frame: 1 month
Heart Failure
Time frame: 1 month
Hospital admission
New cardiovascular hospital admission
Time frame: 1 month
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