Empyema Following Pneumonectomy for Non Small Cell Lung Cancer (NSCLC)

University Hospital, Gasthuisberg600 enrolled

Overview

Empyema following pneumonectomy for Non Small Cell Lung Cancer (NSCLC) is a known problem that occurs in about 2% of pneumonectomy patients.

The development of an empyema following pneumonectomy is a devastating complication, especially if associated with an underlying fistula. Whilst the perioperative mortality of pneumonectomy overall is now less than 5%, this rises to around 25% when complicated by empyema, and about 50% when associated with fistula. In addition, there is the morbidity and social cost of long-term drainage, chronic sepsis and often multiple operations.

Study Type

OBSERVATIONAL

Enrollment

600

Conditions

Non Small Cell Lung Cancer Lung Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pneumonectomy for NSCLC Exclusion Criteria: * Pneumonectomy for other reasons (infectious pathology, trauma, mesothelioma, ...)

Locations (1)

University Hospital Leuven, Dept. Thoracic Surgery

Leuven, Belgium

Outcomes

Primary Outcomes

Overall survival

overall 5-year survival after empyema following pneumonectomy

Time frame: 5 years from surgery

Secondary Outcomes

incidence rate

incidence of empyema, accompanied with broncho-pleural fistula or not, divided in short term (less than 1 yr postoperatively) and long term (up to 5 years postoperatively) incidence.

Time frame: 1 and 5 years from surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.