Patients who underwent major gastrointestinal surgery is potentially at risk of malnutrition due to reduced oral intake, increased nutritional need, reduced gastrointestinal absorption function, and/or metabolic changes after surgery. The postoperative malnutrition is associated with low quality of life and seems to be related long-term nutritional status. This study is a multicenter, open-labeled prospective randomized clinical trial to examine the effect of postoperative oral nutritional supplements (ONS) after major gastrointestinal surgery by comparing the change of body weight and other nutritional parameters between the experiment group that is supplied with ONS and the control group without ONS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
174
Seoul National University Hospital
Seoul, South Korea
Body weight decrease rate 8weeks after discharge compared with preoperative body weight
Time frame: 8weeks after discharge
Changes in body weight before and after surgery
Time frame: preoperatively, at the time of discharge, and 2,4, 8 weeks after discharge
Change of body mass index before and after surgery
Time frame: preoperatively, at the time of discharge after surgery, and 8 weeks after discharge
changes in PG-SGA score and grade
Time frame: preoperatively, and 2,4,8 weeks after discharge
serum hemoglobin
Time frame: preoperatively, at the time of discharge, 2,4,8 weeks after discharge
serum total lymphocyte count
Time frame: preoperatively, at the time of discharge, 2,4,8 weeks after discharge
serum total cholesterol
Time frame: preoperatively, at the time of discharge, 2,4,8 weeks after discharge
serum total protein
Time frame: preoperatively, at the time of discharge, 2,4,8 weeks after discharge
serum albumin
Time frame: preoperatively, at the time of discharge, 2,4,8 weeks after discharge
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