Prevalence of HbA1C in Women With PCOS

Southern Cross Fertility Centre300 enrolled

Overview

Women with PCOS have been observed to be potential diabetics.Recently,American Diabetes Association has suggested screening of women with PCOS for HbA1C.

In view of recent suggestion of American Diabetes Association(ADA)to screen women with PCOS for HbA1C,we intend to study its prevalence in all categories of obesity in women with PCOS. Women with PCOS by Rotterdam criteria will be screened for insulin resistance by using different techniques or tests. Further, the sensitivity and specificity of HbA1C will be compared with sensitivity and specificity of other insulin resistance markers such as OGTT, Free androgen index, free testosterone, fasting insulin to glucose ratio, HOMA-IR and HOMA-B-CELL.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Polycystic Ovarian Syndrome Pelvic Endometriosis Insulin Resistance Non-insulin Dependent Diabetes Mellitus Tubal Obstruction

Eligibility

Sex: FEMALEMin age: 15 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. BMI of 25-35 Kg/Mt2 2. Atleast three of the Rotterdam criteria for diagnosis of PCOS. 3. Subjects with well stabilized Thyroid,if they had documented evidence of previousthyroid disorder. Exclusion Criteria: 1. Subjects with documented diagnosis of Metabolic Syndrome. 2. Subjects with laparocopic and histopathologic diagnosis of Endometriosis. 3Subjects with Primary hyperprolectineamia. 4.Subjects with basal FSH \>/=15mIU/ml. 5.Subjects with continuously elevated 17-0h-p.

Locations (1)

Southern Cross Fertility Centre

Mumbai, Maharashtra, India

Outcomes

Primary Outcomes

Prevalence of HbA1C in both arms of the cohort of subjects

HbA1C has been suggested as a potential marker for NIDDM in subjects with PCOS

Time frame: September 2013

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.