Inhalation of Lidocaine Before Intubation

New Taipei City Hospital70 enrolled

Overview

We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.

Sudden increases in blood pressure and heart rate after tracheal intubation and post-operative sore throat are two common undesirable side effects of general anesthesia and might lead to patients' morbidity or dissatisfaction. We investigated the possibility to attenuate both side effects with one single method, i.e. ultrasound-driven lidocaine inhalation immediately before induction.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Sore Throat

Interventions

Lidocaine inhalationDRUG

Lidocaine inhalation before intubation

PlaceboDRUG

Eligibility

Sex: ALLMin age: 20 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status I or II. Patients scheduled for elective surgery under general anesthesia with orotracheal intubation Exclusion Criteria: * patient's refusal to join, major surgery or expected operation duration longer than 3 hours, patients with a anticipated difficult airway, requiring a nasogastric tube in peri-operative stage, having recent upper respiratory tract infection (within 1 week) or pre-existing sore throat.

Locations (1)

New Taipei City Hospital

New Taipei City, Taiwan

RECRUITING

Outcomes

Primary Outcomes

Blood pressure

Non invasive blood pressure every min for 3 min

Time frame: 3 min

Secondary Outcomes

Post operative sore throat

Questionnaire for Post operative sore throat

Time frame: 3 days

Central Contacts

Chen Yen Po, MD

CONTACT

drbrianchan@yahoo.com.tw

Data from ClinicalTrials.gov

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