Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional femoral/sciatic block combinations effectively reduce postoperative pain, but results in considerable motor blockade. The investigators aimed to evaluate postoperative pain relief and the degree of motor block with block combinations of femoral nerve (FEM) and obturator \[posterior branch\] nerve (ONP), versus saphenous nerve (SAPH) and ONP, versus placebo blocks with isotonic saline. All patients received standard patient controlled analgesia with morphine.Randomized, placebo-controlled and double-blinded clinical trial. Following IRB approval, 81 patients were planned to be randomized to one of three USG block combinations: Active FEM+ONP, active SAPH+ONP or no active blocks (sham blocks) Ropivacaine 0.75% was used for all active blocks following induction of general anaesthesia \[propofol-remifentanil, laryngeal mask airway\]. Primary outcome measure: Localized PACU pain scores (AUC) 0-6 hours postoperatively at rest. Secondary outcome measures: Opioid consumption, opioid related side effects, PACU time, motor abilities of daily living scores \[modified Barthel/100 index\], perceived ill health \[Short form-8\] scores and degree of motor blockade \[Jensen- Børglum motor test\].
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
82
Bispebjerg Hospital, department of anesthesiology
Copenhagen, Denmark
NRS (pain score)
Numerical rating scale(0-10)
Time frame: Area under the curve (AUC) 0-6 hours postoperatively
Opioid consumption
Opioid consumption (PCA pump - mg of morphine)
Time frame: 0-6 hours postoperatively
opioid related side effects
Nausea (0-3), vomiting (\>10 ml)
Time frame: 0-6 hours postoperatively
PACU time
Minutes in PACU
Time frame: 0-6 hours postoperatively
Motor abilities of of daily living
Modified Barthel/100 index
Time frame: 0-24 hours postoperatively
Perceived ill health
Short-Form-8
Time frame: 0-24 hours postoperatively
Degree of motor block.
Jensen-Borglum motor test
Time frame: 0-6 hours postoperatively
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