Association of Carotid Arterial Circumferential Strain With Left Ventricular Function and Hemodynamic Compromise During Off-pump Coronary Artery Bypass Surgery

Yonsei University96 enrolled

Overview

This study is aimed to evaluate the association of common carotid artery circumferential strain with the echocardiographic parameters of left ventricular function and the degree of actual hemodynamic deterioration in patients undergoing multi-vessel off-pump coronary artery bypass with preserved left ventricular ejection fraction.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Three Vessel Coronary Artery Disease

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. three vessel coronary artery disease 2. sinus rhythm Exclusion Criteria: 1. New York Heart Association functional class ≥3 2. known pulmonary hypertension 3. known valvular heart disease 4. serum creatinine ≥2.0 mg/dL 5. myocardial infarction within 1 week before the surgery 6. history of cerebral or peripheral arterial occlusive disease

Locations (1)

Yonsei University College of Medicine

Seoul, Seoul, South Korea

Outcomes

Primary Outcomes

TTE parameters

TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em

Time frame: 1 day before the surgery

Secondary Outcomes

change of intraoperative hemodynamic variables

TTE parameters: left ventricular ejection fraction, left atrial volume index, left ventricular mass, Sm, Em, E/Em Carotid circumferential strain : Storage of transverse image of the right CCA at approximately 1cm proximal to the bifurcation, manual trace of luminal-intimal border and automatic tracking by frame-to-frame movement of ultrasound reflections (speckles) Hemodynamic variables: cardiac index and mixed venous oxygen saturation obtained from the pulmonary artery catheter and cardiac output monitoring devices

Time frame: from after induction of anesthesia, left circumflex artery grafting, and to sternum closure

Data from ClinicalTrials.gov

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