Impact of an Antioxidant Alimentary Complement on Sperm Data

Centre Hospitalier Universitaire de Nice200 enrolled

Overview

Male infertility is a multifactorial disease process with a number of potential contributive causes. Considering the majority of male infertility cases are due to deficient sperm production of unknown origin, environmental and nutritional factors must be evaluated. The purpose of this study is to evaluate the effects of 6 months antioxidant dietary complement (Conceptio) on sperm parameters (sperm count, motility and DNA fragmentation) in infertile men with oligoasthenozoospermia.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Infertility

Interventions

Conceptio EADRUG

The patients are included during a consultation whether it is with a clinician or a biologist of the Center. It is suggested in routine in the service, to all the patients consulting for a problem of infertility and presenting pathological spermatic data, taking the food complement Conceptio. At the patients wishing to take this complement it will be suggested participating in this study. This complement is usually bought by the patient, within the framework of this study this one will be gracefully supplied. The follow-up of the patient will contain no examination and no anybody visit besides the usually realized follow-up.

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Number of sperm cells \< 15M / mL and\\or mobility \< 40 %. * Signature of a form of not opposition to the research. * Membership in a social security system. Exclusion Criteria: * Number of sperm cells = 100M / mL.

Locations (1)

CHU de Nice - Hôpital de l'Archet

Nice, Alpes-Maritimes, France

Outcomes

Primary Outcomes

Spermatic parameters (numeration and mobility spermatic)

The spermatic parameters used within the framework of the spermogramme made in routine in the Laboratory of Biology of the Reproduction will be the numeration and the spermatic mobility from the very beginning.

Time frame: At the inclusion and 6 months after the inclusion

Secondary Outcomes

Rate of fragmentation of the DNA

We shall consider the rate of fragmentation of the DNA determined according to the method of the TUNEL. This technique allows to estimate the rate of spermatozoides apoptose. It brings to light the fragmentation of the spermatic DNA in the course of process of cellular death.

Time frame: At the inclusion and 6 months after the inclusion

Data from ClinicalTrials.gov

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