Mesalamine in Environmental Enteropathy

Inclusion Criteria: * Children aged 1 to 5 years old. * Provision of informed consent by parent or guardian. * Stunting (height for age z score \<-2) * Severe malnutrition (one or more of mid-upper arm circumference \<11.5cm, weight for height z score \<-3, or nutritional oedema). * Eligible for outpatient management of malnutrition (i.e. no evidence of acute infection, and passes 'appetite test' according to national guidelines). * Evidence of chronic inflammation (elevated erythrocyte sedimentation rate, ESR \>20mm/hr). Exclusion Criteria: * Known HIV disease or tuberculosis. * Known previous renal disease or asthma. * Known allergy or hypersensitivity to mesalamine, other salicylate drugs, or any of the product ingredients. * Biochemical evidence of acute renal or hepatic impairment on screening blood tests. * Thrombocytopenia * Recent (previous two weeks) bloody diarrhoea. * Concurrent medication known to interact with the study drug (non-steroidal anti-inflammatory drugs, ranitidine, proton-pump inhibitors) * Acute infection requiring treatment, e.g. lower respiratory tract infection or febrile illness. * Other reason at the discretion of the attending clinician (independent of the trial team).