Screen-and-treat approach reduces postabortal pelvic inflammatory disease after induced abortion, and at the same time alters women's sexual behavior and prevents further re-infection by sexually transmitted infections when compared to the universal antibiotic prophylaxis strategy.
While universal antibiotic prophylaxis during induced abortion has been proven to reduce postabortal pelvic inflammatory diseases, screen-and-treat approach has the potential benefit of altering women's sexual behavior and preventing further re-infection by sexually transmitted infections. We conducted a randomized controlled trial to compare the effect of the two approaches in preventing postabortal pelvic inflammatory disease and the women's sexual behavior.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
2,193
100 mg twice daily for 7 days starting on the day of induced abortion
Specific antibiotic treatment was only given if the women was found to have sexually transmitted infection(s) on screening.
Queen Mary Hospital
Hong Kong, Hong Kong, China
Rate of postabortal inflammatory disease 6 weeks after induced abortion.
Time frame: 6 weeks after induced abortion.
Rate of re-infection by sexually transmitted infections 24 weeks after induced abortion.
Time frame: 24 weeks after induced abortion.
Proportion of women having abstinence from sexual intercourse or using condom at 6 weeks, 24 weeks and 1 year after induced abortion.
Time frame: 6 weeks, 24 weeks and 1 year after induced abortion
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