Urgency Incontinence (where the bladder muscles contract suddenly, causing an immediate urge to urinate that is difficult to prevent) is commonly experienced in patients with overactive bladder. New findings have discovered that urgency incontinence may be connected to the interactions of certain regions of the brain and the bladder. Although this is a common problem, researched still do not know how these interactions impact the process of urgency incontinence. Furthermore, there is preliminary data to suggest that interventions such as Mindful-Based Stress Reduction (MBSR) can potentially be used as therapy for UI. The purpose of this study is to determine the impact MBSR training on UI symptoms, quality of life, and anxiety measures.
Urgency Incontinence (where the bladder muscles contract suddenly, causing an immediate urge to urinate that is difficult to prevent) is commonly experienced in patients with overactive bladder. New findings have discovered that urgency incontinence may be connected to the interactions of certain regions of the brain and the bladder. Although this is a common problem, researched still do not know how these interactions impact the process of urgency incontinence. Furthermore, there is preliminary data to suggest that interventions such as Mindful-Based Stress Reduction (MBSR) can potentially be used as therapy for UI. The purpose of this study is to determine the impact MBSR training on UI symptoms, quality of life, and anxiety measures. To determine the impact of MBSR training on Urinary Incontinence(UI) symptoms, quality of life and anxiety measures in women affected with UI. We hypothesize that participants will have significant improvement in UI and anxiety related symptoms and quality of life measures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
12
The MBSR course developed by Jon Kabat-Zinn is a mind-body intervention that incorporates mindfulness techniques. This is an eight week MBSR course at OHSU. Class instruction will be augmented by daily home practices of listening to audiotapes, diary reflections, and reading preloaded on itouch devices provided to participants. Adherence will be assessed through in-house iMINDr tracking program loaded on the itouch.
Oregon Health Science University
Portland, Oregon, United States
Change in Functional Magnetic Resonance Imaging (fMRI)
To use advanced brain imaging techniques, namely functional MRI (fMRI) to determine whether change in Urinary Incontinence and anxiety symptoms after a Mindfulness Based Stress Reduction course are associated with changes in activation patterns in the brain.
Time frame: Administered before and within 6 weeks after participation in the MBSR course
Change in Overactive Bladder Symptom and Quality of Life Short Form
A questionnaire validated for overactive bladder patients that includes symptom bother and health-related quality-of-life questions
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Patient Global Impression of Severity and Improvement
single-question global indexes for Urinary Incontinence severity and improvement
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Beck Anxiety Inventory
A self-report questionnaire for anxiety consisting of 21 items with items describing physical, physiological and cognitive aspects of anxiety
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Mindfulness Attention Awareness Scale
A 15 item trait measure of the tendency to attend to present moment experiences in everyday activities
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Perceived Stress Scale
A 10 item self report questionnaire aimed to tap experiences of distress related to 'how unpredictable, uncontrollable, and overloaded respondents find their lives
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Urogenital Distress Inventory - Short Form
A 6 item self report questionnaire with items assessing life quality and symptom distress for urinary incontinence
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Urinary Incontinence Episodes in 3-Day Period
Subjects will be asked to keep a diary that tracks their bladder and urinary habits for 3 days
Time frame: Administered before and within 6 weeks after participation in the MBSR course. Repeated between 6-8 months post intervention
Change in Resting State Functional Connectivity Magnetic Resonance Imaging (rs-fcMRI)
To use advanced brain imaging techniques, namely functional connectivity MRI to determine whether change in Urinary Incontinence and anxiety symptoms after a Mindfulness Based Stress Reduction course are associated with changes functional connectivity patterns in the brain.
Time frame: Administered before and within 6 weeks after participation in the MBSR course
Change in Diffusion Tensor Imaging (DTI)
To use advanced brain imaging techniques, namely diffusion tensor Imaging(DTI) to assess white matter integrity and fiber tracking.
Time frame: Administered before and within 6 weeks after participation in the MBSR course
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