The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and recovery time in male amateur sportsmen with medium proficiency level compared to placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
69
Sportschule FFb Puch GmbH
Fürstenfeldbruck, Germany
Reduction of maximal concentric strength, movement induced pain and pressure induced pain combined in a multidimensional (composite outcome)model giving information about the change induced by the stress test
Multidimensional approach for recovery and acute phase after eccentric stress test. Will be assessed at different time points before and after an excentric stress test and the reduction of these parameters under treatment will be calculated.
Time frame: immediately before, 24h post, 48h post
Maximal concentric strength (Nm) before and after the stress test
Reduction of strength induced by the excentric stress test
Time frame: immediately before, 0h, 3h, 6h, 24h, 48h, 72h
Pressure induced pain
Pain induced by the stress test rated via Algometry kg/cm\*cm induced by standardised pressure
Time frame: immediately before, 0h, 3h, 6h, 24h, 48h, 72h
Blood routine parameters
Blood routine parameters (differentiated haemogram; blood lipids; glucose; kreatinin) as safety parameters
Time frame: immediately before, 0h, 3h, 6h, 24h, 48h, 72h
blood pressure
Blood pressure and heart rate as safety parameter
Time frame: immediately before, 24h, 48h, 72h
Movement induced pain
Pain induced by a standardised movement and rated by the volunteer via VAS.
Time frame: immediately before, 0h, 3h, 6h, 24h, 48h, 72h post
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