The Effect of「GTT-EGCG」on Acne Women

National Yang Ming Chiao Tung University80 enrolled

Overview

The aim of this study is to investigate the therapeutic effects of green tea extract on acne treatment and related hormone peptides by a double-blinded, randomized and controlled clinical trial.

change in acne lesions counts, hormone, quality of life

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Acne Lesion Counts

Interventions

green tea extract EGCGDIETARY_SUPPLEMENT

EGCG, 500mg, tid, 4 weeks

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Female patient * 20 to 45 years of age * moderate or severe acne vulgaris as defined by the Investigator's Global Assessment (IGA; score of 3 or 4 on a scale from 0 to 5) Exclusion Criteria: * Received systemic retinoid or hormone treatment in the previous 3 months. * Abnormal liver enzymes or kidney function tests (1.5 times higher than the upper normal limit) * abnormal blood chemistry * Pregnant or breast feeding women or the intention of becoming pregnant * Concurrent systemic illness * PCOS * Very severe acne(IGA score5)

Locations (1)

Taipei City Hospital

Taipei, Taiwan, Taiwan

Outcomes

Primary Outcomes

acne lesion counts

Time frame: four weeks

Secondary Outcomes

quality of life, SF-12

Time frame: four weeks

Data from ClinicalTrials.gov

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