AcoArt Ⅰ / SFA China

Inclusion Criteria: * Age between 18 and 80 years * Patients with peripheral artery disease (PAD), with Rutherford classification between 2 and 5 * an occlusion or a minimum grade of stenosisPrimary over 70% in the superficial femoral artery an /or the popliteal artery * Total length of treat lesion(s)is less or equal to 40cm * signed Patient informed consent form Exclusion Criteria: * plasma Cr level greater than 150 umol/L in patients * patients with acute thrombosis requiring lysis or thrombectomy * patient with a lysis or an lower limb intervention as a therapy within the last 6 weeks * patient requiring intervention in both lower limbs at the same time * target lesion can't be cross by the guide wire * distal outflow through less than one lower leg vessel * known hypersensitivity to aspirin, heparin, clopidogrel,paclitaxel, contrast medium, etc. * patients participating in another clinical trials with interfere with this trial in the past 3 months * pregnancy and lactating woman * untreatable bleeding diatheses * other diseases, such as cancer, liver disease, or cardiac insufficiency, which may lead to protocol violations or markedly shorten a patients's life expectancy(less than 2 years) * patients unable or unwilling to participate this trial