The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)

University of Virginia24 enrolled

Overview

The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy

The management of intracranial hypertension requires the presence of an intracranial pressure monitor. We are investigating whether the waveforms obtained from a near infrared spectroscopy device can predict what the intracranial pressure is non-invasively. * Patients with intracranial hypertension who are intubated and ventilated in the ICU will be recruited * we will record there intracranial pressure and systemic arterial pressure * recordings from the near infrared device will be recorded and analysed off-line * we will correlate the waveform tracings from near infrared spectroscopy and the arterial tracing

Study Type

OBSERVATIONAL

Enrollment

Conditions

Intracranial Hypertension

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients with an intracranial pressure monitor and arterial catheter who are admitted to the ICU Exclusion Criteria: Less than 18 years

Locations (1)

University of Virginia

Charlottesville, Virginia, United States

Outcomes

Primary Outcomes

Intracranial elastance

Intracranial elastance (δP/δV)will be measured by dividing the pulse pressure of an invasive arterial blood pressure by the amplitude of high frequency oscillations in the near infrared (NIR) absorbance waveforms.

Time frame: Participants will be followed while an arterial line and intracranial pressure monitor is present duing the ICU admission. This is expected to be an average of 5 days.

Data from ClinicalTrials.gov

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