The hypothesis is: In patients after an out of hospital cardiac arrest, treated with therapeutic hypothermia (33°C) will be found significantly more microcirculatory abnormalities, compared to the same group of patients treated with 36°C.
The purpose of this study is to investigate the (sublingual) microcirculation in patients after an out of hospital cardiac arrest (OHCA). The microcirculation is measured in this study by Sublingual Side Stream Darkfield (SDF) Imaging and Near InfraRed Spectroscopy (NIRS) at admission and after 12 and 24 hours.
Study Type
OBSERVATIONAL
Enrollment
22
at baseline, after 12 and 24 hours in both arms
Medical Center Leeuwarden
Leeuwarden, Netherlands
Microvascular Flow Index (MFI)
Microvascular Flow Index; minimum score = 0 (= no flow) and maximum score = 3 (=normal flow)
Time frame: baseline measurement
RincStO2
tissue oxygenation measured by Near Infrared Spectroscopy
Time frame: baseline
Fluid Balance After 24 Hours
Time frame: 24 hours
Inotropes and Vasopressor Dose
Time frame: baseline
Cardiac Index
Cardiac Index is cardiac output indexed for body weight
Time frame: 24 hours
Lactate
lactate levels in serum
Time frame: 24 hours
SvO2
(venous oxygen saturation)
Time frame: 24 hours
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