The study investigates the time to engraftment of a mesenchymal expanded cord blood unit in patients with hematologic malignancies undergoing transplantation with myeloablative conditioning.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
49
Infusion of one MPC expanded cord unit and one unexpanded cord unit.
Umbilical Cord Blood.
University of Miami Health System Sylvester Comprehensive Cancer Center
Miami, Florida, United States
Moffitt Cancer Center
Tampa, Florida, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Time to Neutrophil and Platelet Engraftment
Time frame: 100 days
Proportion of subjects with neutrophil recovery at day 26, platelet recovery at day 60 and subjects alive at day 100
Time frame: 100 days
Percentage of patients with primary graft failure
Time frame: 100 days
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