Surgical Treatment in Diabetic Patients With Grade 1 Obesity

Inclusion Criteria: * Man or woman with Type 2 diabetes mellitus (DM) aged between 25 and 65 years, with time since diagnosis of diabetes less than 10 years. * Grade I obesity (BMI between 30-35) * Inadequate glycemic control with HbA1c between 7.0 to 9.5% at baseline, in the presence of drug treatment for diabetes in the last year. * Reserve pancreatic C-peptide\> 1.0 at baseline. * Overweight stable defined as BMI\> 30 in the last two years. Exclusion Criteria: * History ketoacidosis, diabetes mellitus type 1, diabetes followed by pancreatitis. * Repetition of measurements (ie, 2 or more within 1 week) fasting plasma glucose(FPG) \> 240 mg / dL during the pre-treatment. * History of Severe Proliferative Diabetic Retinopathy. * Autonomic neuropathy. * Loss or gain significant weight within the last 12 weeks (range, 5% body weight) * Renal insufficiency * History of renal disease treated with immunosuppressive therapy, history of dialysis or kidney transplantation. * Presence of other renal diseases (eg nephrotic syndrome, glomerulonephritis) * Acute myocardial infarction, unstable angina (NYHA class III-IV), revascularization or stroke within the previous 3 months of the initial visit. * Uncontrolled hypertension defined as diastolic blood pressure\> 100mm/Hg and diastolic blood pressure\> 160mm/Hg at the initial visit. * History of Hepatitis B or Hepatitis C. * Criteria for Hepatic insufficiency defined as Child B and C liver disease clinically active and aspartate aminotransferase (AST) and alanine aminotransferase (ALT) above 3 times the upper limit of normal. * History of prior bariatric surgery. * Inflammatory Bowel Disease. * History neoplasm within the last 5 years (except for squamous cell carcinoma and basal skin and cervical carcinoma in situ) * Clinically important hematologic disorder (symptomatic anemia, bone marrow proliferative disorders, thrombocytopenia, ..) * History antibody positive human immunodeficiency virus (HIV) * Surgery with general anesthesia within 12 weeks prior to the initial visit or incomplete recovery from prior surgery. * History of drug or alcohol abuse within 3 years before the initial visit. * Pregnancy or breastfeeding or planning pregnancy in the next two years.