This study is designed to investigate whether the pupil response to slowly flashing colored lights is significantly altered in patients with glaucoma, as compared to a control group of subjects without glaucoma.
The pupils inside the eyes constrict in response to light stimulation. Different classes of cells within the human retina initiate this response. Recent research suggests that one of the ganglion cell types involved in this pupil response is affected by glaucoma. By measuring pupil responses to different colored lights, the function of this class of cells can be evaluated quickly, and without touching the eye. An advantage of pupil testing strategies is that they do not require subjective feedback from the subject about what they can see, as is required for standard visual field tests that are used in the clinic. The main aim of this study is to measure and compare the pupil constriction that occurs in response to flickering red and blue lights in patients with glaucoma versus matched control patients without glaucoma. In addition, the subjects will be asked questions about their quality of life and it will be determined whether issues related to quality of life correlate to alterations in the pupil responses.
Study Type
OBSERVATIONAL
Enrollment
32
OSU College of Optometry
Columbus, Ohio, United States
Havener Eye Institute
Columbus, Ohio, United States
Pupil Response
Using fourier analysis, the pupil fluctuation evoked by blue and red flickering lights will be measured in glaucoma patients and compared to matched controls.
Time frame: Single Visit: One Day
Quality of Life Survey
Subjects will fill out a questionnaire with questions that assess quality of life issues, and the results will be correlated to the pupil response data.
Time frame: Single Visit: One Day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.